Enhancing togetherness: kinetochores and cohesion
نویسندگان
چکیده
منابع مشابه
Enhancing togetherness: kinetochores and cohesion.
All organisms must correctly copy and equally distribute their genetic information each and every time a new cell is created. In eukaryotic cells, this action involves many different coordinated processes, including DNA replication, kinetochore and spindle formation, and chromosome cohesion. If errors occur in chromosome segregation, a chromosome may be lost or gained, resulting in an aneuploid...
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Not to be confused with1⁄4 centrosomes. But it’s OK to confuse them with centromeres. The centromere is the chromosomal domain where the kinetochore is assembled. Genetically speaking, the centromere is the locus necessary to segregate chromosomes. In many species, the centromere is also defined cytologically as the primary constriction visible on condensed chromosomes (the intersection point o...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2007
ISSN: 0890-9369
DOI: 10.1101/gad.1523107